Cell Competition for Survival and Proliferation Resources Defines the CD4+ T Cell Niche

Cell Competition for Survival and Proliferation Resources Defines the CD4+ T Cell Niche
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Published on 2006 by ProQuest

This ebook tells about The two critical hallmarks of adaptive immunity to infectious disease are a diverse antigen receptor repertoire and the memory of which antigen receptors have proven most useful. The CD4+ T cell plays a central role in adaptive immunity to the extent that it provides signals for the function or survival of many other cells in the immune system, including other CD4+ T cells, CD8+ T cells, B cells, and antigen-presenting cells such as macrophage. Although it is known how antigen receptor repertoire diversity is produced, whether mechanisms exist to maintain the survival of a diverse T cell repertoire has not been well addressed by the field. In addition, the conditions required for the generation and maintenance of antigen-specific memory CD4+ T cells are largely unknown.

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Cell Competition for Survival and Proliferation Resources Defines the CD4+ T Cell Niche
\u003cb\u003esurvival resources\u003c/b\u003e away from a much more rare naive cell that might turn out to \u003cbr\u003e\nbe lifesaving next week. What is the form of regulation that allows the immune \u003cbr\u003e\nsystem to balance the opposing needs of diversity and memory to result in ...

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